Agasti 17, 2015 |Amathuluzi nemishini, Amathuluzi aselabhorethri nemishini yaselabhorethri, Izindaba Zaselabhorethri, Izinqubo zaselabhorethri, Izifo Zaselabhorethri, Ukuhlolwa kwaselabhorethri
Ngokubeka le divayisi engabizi yokusetshenziswa okukodwa, eyakhiwe eNyuvesi yaseWisconsin-Madison, engalweni noma esiswini, iziguli zingakwazi ukuqoqa igazi lazo ekhaya ngemizuzu.
Sekuyiminyaka engaphezu kwemibili, abezindaba baseMelika bewuthakasele umqondo we-Theranos CEO u-Elizabeth Holmes wokunikeza iziguli ezidinga ukuhlolwa kwegazi ukuhlolwa kwegazi ngomunwe esikhundleni se-venipuncture.Ngaleso sikhathi, amalebhu ocwaningo ezweni lonke asebenzela ukuthuthukisa izindlela zokuqoqa amasampula okuhlolwa kwelebhu yezokwelapha ezingadingi izinaliti nhlobo.
Ngomzamo onjalo, ingangena emakethe ngokushesha okukhulu.Lena idivayisi yokuqoqa igazi engenanaliti ebizwa ngokuthi i-HemoLink, eyakhiwe ithimba labacwaningi eNyuvesi yaseWisconsin-Madison.Abasebenzisi bavele babeke idivayisi elingana nebhola legalofu engalweni noma esiswini sabo imizuzu emibili.Ngalesi sikhathi, idivayisi idonsa igazi kuma-capillaries liyise esitsheni esincane.Isiguli sizobe sesithumela ishubhu legazi eliqoqiwe elabhorethri yezokwelapha ukuze lihlaziywe.
Le divayisi ephephile ilungele izingane.Kodwa-ke, iziguli ezidinga ukuhlolwa kwegazi njalo ukuze ziqaphe impilo yazo nazo zizozuza njengoba kuzisindisa ohambweni oluvamile lwamalebhu omtholampilo ukuyodonsa igazi ngendlela evamile yokuhlaba inaliti.
Enqubweni ebizwa ngokuthi “isenzo se-capillary,” i-HemoLink isebenzisa i-microfluidics ukuze idale i-vacuum encane edonsa igazi kuma-capillary ngokusebenzisa imigudu emincane esikhumbeni iye kumashubhu, kubika i-Gizmag.Idivayisi iqoqa 0.15 cubic amasentimitha igazi, okwanele ukubona cholesterol, izifo, amangqamuzana omdlavuza, ushukela wegazi nezinye izimo.
Odokotela bezifo kanye nochwepheshe belebhu yomtholampilo bazobe bebukele ukwethulwa kokugcina kwe-HemoLink ukuze babone ukuthi abathuthukisi bayo bazinqoba kanjani izinkinga ezithinta ukunemba kokuhlolwa kwaselabhorethri ezingabangelwa uketshezi lwangaphakathi oluvame ukuhambisana negazi le-capillary lapho kuqoqwa amasampula anjalo.Ukuthi ubuchwepheshe bokuhlola ngelebhu obusetshenziswa i-Theranos bungaxazulula kanjani inkinga efanayo kube yinto okugxilwe kuyo amalebhu ezokwelapha.
I-Tasso Inc., isiqalo sezokwelapha esathuthukisa i-HemoLink, yasungulwa abacwaningi abathathu bangaphambili be-UW-Madison microfluidics:
I-Casavant ichaza ukuthi kungani amandla amancane e-microfluidic esebenza: “Kulesi silinganiso, ukungezwani kwendawo kubaluleke kakhulu kunamandla adonsela phansi, futhi kugcina igazi lisesiteshini kungakhathaliseki ukuthi ulubamba kanjani umshini,” esho embikweni we-Gizmag.
Lo msebenzi uxhaswe ngezigidi ezintathu zamaRandi yi-Defence Advanced Research Projects Agency (DARPA), uphiko locwaningo loMnyango Wezokuvikela wase-United States (DOD).
Abasunguli abathathu be-Tasso, Inc., abacwaningi bangaphambili be-microfluidics e-University of Wisconsin-Madison (kusuka kwesobunxele kuya kwesokudla): U-Ben Casavant, Iphini Likamongameli Wezokusebenza Nobunjiniyela, u-Erwin Berthier, iPhini Likamongameli Wezokucwaninga Nokuthuthukiswa Nobuchwepheshe, kanye no-Ben Moga, uMongameli, esitolo sekhofi bathole umqondo we-HemoLink.(I-copyright yesithombe i-Tasso, Inc.)
Idivayisi ye-HemoLink ishibhile ukuyikhiqiza futhi i-Tasso inethemba lokuthi izotholakala kubathengi ngo-2016, ngokusho kweGizmag.Kodwa-ke, lokhu kungase kuncike ekutheni ososayensi be-Tasso bangakwazi yini ukuthuthukisa indlela yokuqinisekisa ukuzinza kwamasampula egazi.
Njengamanje, amasampula egazi amaningi okuhlolwa kwelabhorethri yomtholampilo adinga ukuthuthwa ngeketango elibandayo.Ngokombiko we-Gizmag, ososayensi be-Tasso bafuna ukugcina amasampula egazi ku-140 degrees Fahrenheit isonto lonke ukuze baqinisekise ukuthi ayahlolwa uma befika elebhu yasemtholampilo ukuze icutshungulwe.UTasso uhlela ukufaka isicelo semvume ye-US Food and Drug Administration (FDA) ekupheleni kwalo nyaka.
I-HemoLink, idivayisi yokuqoqa igazi engenanaliti engabizi kakhulu elahlwayo, ingase itholakale kubathengi ngo-2016. Isebenzisa inqubo ebizwa ngokuthi "isenzo se-capillary" ukuze idonse igazi eshubhuni yokuqoqa.Abasebenzisi bavele balibeke engalweni noma esiswini imizuzu emibili, ngemuva kwalokho ishubhu lithunyelwa elebhu yezokwelapha ukuze lihlaziywe.(I-copyright yesithombe i-Tasso, Inc.)
I-HemoLink yizindaba ezinhle kubantu abangazithandi izinti yenaliti nabakhokhi abanendaba nokwehlisa izindleko zokunakekelwa kwempilo.Ngaphezu kwalokho, uma i-Tasso iphumelela futhi yamukelwa yi-FDA, ingase futhi inikeze abantu emhlabeni wonke - ngisho nasezindaweni ezikude - ikhono lokuxhuma kumalebhu amaphakathi okuhlola igazi futhi bazuze ekuxilongweni okuthuthukile.
"Sinedatha ephoqayo, ithimba labaphathi abanolaka kanye nezidingo zomtholampilo ezingafinyeleli emakethe ekhulayo," kusho uModja embikweni weGizmag."Ukukala ukunakekelwa kwasekhaya ngeqoqo legazi eliphephile nelilula ukuze kuhlonzwe umtholampilo kanye nokuqapha kuwuhlobo olusha olungathuthukisa imiphumela ngaphandle kokwenyusa izindleko zokunakekelwa kwezempilo."
Kodwa akubona bonke ababambiqhaza embonini yelabhorethri yezokwelapha abazojabula ngokwethula imakethe ye-HemoLink.Ubuchwepheshe obungase bushintshe umdlalo wawo womabili amalabhorethri omtholampilo kanye nenkampani ye-biotech yase-Silicon Valley, i-Theranos, echithe izigidi zamadola ithuthukisa indlela eyenza ngayo ukuhlolwa kwegazi okuyinkimbinkimbi kusukela kumasampula egazi aphethwe ngomunwe, kubika i-USA TODAY.
Kungaba indida uma abathuthukisi be-HemoLink bengaxazulula noma yiziphi izinkinga ngobuchwepheshe babo, bathole imvume ye-FDA, futhi balethe ukumaketha umkhiqizo phakathi nezinyanga ezingama-24 ezizayo okususa isidingo sokuthatha amasampula eminwe.Izinhlobo eziningi zokuhlolwa kwelabhorethri yezokwelapha.Lokhu nakanjani kuzontshontsha “ukuduma okukhulu” okuvela eTheranos, osekuyiminyaka emibili edlule beveza umbono wabo wokuguqula imboni yokuhlola ilebhu yasemtholampilo njengoba isebenza namuhla.
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Angiqiniseki ukuthi lokhu kusebenza kahle kangakanani - I-Theranos ayikhiphi imininingwane eminingi.Ezinsukwini ezimbalwa ezedlule, bathole nezaziso zokuyeka nokuyeka.Ukuqonda kwami ​​le mishini ukuthi zisebenzisa “ama-clumps” aphezulu ama-capillary asebenza njengezinaliti.Angase ashiye amabala abuhlungu, kodwa angicabangi ukuthi ukungena ngokuphelele esikhumbeni kujule njengenaliti (isb. Akkuchek).